Articulo IGF y su Relación con características de crecimiento

POLYMORPHISMS IN IGF1 GENE AND THEIR EFFECT ON GROWTH TRAITS IN MEXICAN BEEF CATTLE


Xochitl De la Rosa Reyna
Humberto Martínez Montoya
Victoria Valerio Castrellón
Ana M. Sifuentes Rincón
Manuel Parra Bracamonte
Williams Arellano Vera

ABSTRACT

The IGF1 gene (insulin-like growth factor 1) is a candidate gene for marker-assisted selection strategies. A SNP in the promoter region (IGF1/Sna BI) has been reported and associated with production traits in several cattle breeds. Here, we report its allelic frequencies evaluated in Charolais and Beefmaster breeds, and confirm its association with three growth traits: weaning weight (PD), weaning weight adjusted to 210 days (P210) and preweaning weight gain (GPD) in Charolais breed. In addition, we designed a strategy to search in these breeds for a new polymorphism in four coding regions of the gene. A C/A transversion was detected in intron 4, but it did not show an association with the growth traits tested.

The SNP (IGF1/SnaBI), is proposed as a potential selection marker in Mexican Charolais cattle, the validation of its association with PD, P210 and GDP, could complement the genetic evaluations of this breed through marker-assisted management strategies. The characterization of the gene IGF1 in Mexican populations of Beefmaster and Charolais cattle permitted the identification of a new SNP in this gene, which should be the subject of future studies to determine its role as a molecular marker.

Key words: IGF1; SNP IGF1/Sna BI; Polymorphism; Charolais; Beefmaster

Ya en Genetics and Molecular Research Evolution and Technology.
http://www.funpecrp.com.br/gmr2008b/index.asp

Publicación de nuevo artículo.

IMPORTANCIA DE LA VERIFICACIÓN-ASIGNACIÓN DE PROGENITORES EN SISTEMAS EXTENSIVOS DE PIE DE CRÍA Importance of Parentage Verification-Assignment in Extensive Multiple-Sired Breeding Herds.

Williams Arellano-Vera
Ana María Sifuentes-Rincón
Rogelio Garcidueñas-Piña
Gaspar Manuel Parra-Bracamonte

Revista Científica, FCV-LUZ / Vol. XX, Nº 1, 53 - 60, 2010

RESUMEN
Se aplicó un panel de nueve marcadores microsatélites para estructurar la genealogía de un hato de ganado Braford manejado bajo empadre múltiple y destinado a pié de cría, para evaluar las repercusiones de la adecuada asignación de progenitores, así como las implicaciones en su mejoramiento genético. Se logró la asignación de paternidad en el 100% de la progenie, mientras que en los ensayos de verificación de maternidad se estimó un porcentaje de error de asignación de aproximadamente 90%. Los resultados encontrados apoyan el uso de la asignación de paternidad para verificar la estructura genealógica (paternidad y maternidad) de hatos cuya certeza en el pedigrí es crítica para el mejoramiento genético de su raza, y en donde el sistema de manejo extensivo y empadre múltiple limitan el registro adecuado de la progenie al momento del parto.

ABSTRACTTo assess the implications of parentage assignation on herdsgenetic improvement nine microsatellite markers were used in order to structure the genealogy of a multisired Braford herd. All progeny (100%) had satisfactory paternity assignment, conversely the maternity verification analysis showed assignation errors up to 90%. Our results support the use of molecular tools to verify the pedigree structure in those herds with management systems that limit the proper registration of progeny at calving.

http://www.fcv.luz.edu.ve/Pdf/2010/01/articulo7.pdf